Diana Klurfeld has been in the health care industry for well over decade in NYC. Throughout her time in the healthcare industry, Diana has had the opportunity to work alongside of some of the best health care administrators and doctors in the country. Together with her husband, Alex Klurfeld, a trained physical therapist and entrepreneur, Diana has found that regardless of the size or quality of the medical institution, it seems that patient treatment and care suffers from qualitative decline in inverse proportion to the number of people who suffer from that particular ailment. Big Pharma: As Diana Klurfeld has touched upon in many of articles, most of the breakthrough medications and cures for diseases are created in big pharma / biotech companies or research universities. Big Pharma exists largely in the private sector and many biotech funds are publicly traded companies. This means that they have shareholders to answer to and that is their first responsibility. Normally, that's a good thing. This is because shareholder's are best served by pouring cash reserves into R&D to discover the next breakthrough medication that will change patients' lives forever. But for those R&D dollars to have the biggest impact, they will need to cure or treat a disease with the largest patient pool. There is little profit in curing a disease that affects under five million people worldwide, at least not when compared to a disease like cancer which is ubiquitous today. Charitable Organizations: Diana notes that charitable organizations can also play a significant role in raising money for curing and treating diseases. However, like Big Pharma, charities are drawn to large patient populations, thinking that they can help the most people by finding the problem with the most widespread impact. While this is intuitive and, at first blush, seemingly logical, it's also largely incorrect. And that's because diseases and conditions that affect large percentages of the world's population are already adequately funded and their cures are being vigorously researched by universities and big pharma alike. Charitable organizations should fill the void that the private sector, whose primary interest is profit, leaves behind when it focuses to serve the many. Charitable foundations should exist to serve the few. Diana and Alex Klurfeld feel that more charitable foundations will come from spreading the word. It's not that charitable organizations have turned a blind eye to those suffering from "orphan diseases," it's that not enough people know about "orphan diseases" to start coming up with solutions about how they can help. And that's why Alex Klurfeld and his wife, Diana Klurfeld, have started KlurfeldCares.com